USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: RRAS2_HUMAN USC-OGP 2-DE database:  RRAS2_HUMAN RRAS2_HUMAN General information about the entry View entry in simple text format Entry name RRAS2_HUMAN Primary accession number P62070 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Ras-related protein R-Ras2; AltName: Full=Ras-like protein TC21; AltName: Full=Teratocarcinoma oncogene; Flags: Precursor;. Gene name Name=RRAS2 Synonyms=TC21 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1291: pI=5.93; Mw=24593 SPOT OGP-1295: pI=5.53; Mw=24207 Cross-references UniProtKB/Swiss-Prot P62070; RRAS2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name RRAS2_HUMAN Primary accession number P62070 Secondary accession number(s) B2R9Z3 B7Z5Z2 B7Z6C4 B7Z7H6 P17082 Sequence was last modified on  June 21, 2004 (version 1) Annotations were last modified on  March 15, 2017 (version 150) Name and origin of the protein Description RecName: Full=Ras-related protein R-Ras2; AltName: Full=Ras-like protein TC21; AltName: Full=Teratocarcinoma oncogene; Flags: Precursor; Gene name Name=RRAS2 Synonyms=TC21 Encoded on Name=RRAS2; Synonyms=TC21 Keywords 3D-structure; Acetylation; Alternative splicing; Cell membrane; Complete proteome; Disease mutation; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Palmitate; Phosphoprotein; Prenylation; Proto-oncogene; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M31468; AAA36545.1; ALT_FRAME; mRNA EMBL AF493924; AAM12638.1; ALT_FRAME; mRNA EMBL AK299606; BAH13078.1; -; mRNA EMBL AK300103; BAH13210.1; -; mRNA EMBL AK302033; BAH13612.1; -; mRNA EMBL AK313976; BAG36690.1; -; mRNA EMBL AC011084; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471064; EAW68487.1; -; Genomic_DNA EMBL BC013106; AAH13106.1; -; mRNA CCDS CCDS44544.1; -. [P62070-2]; . CCDS CCDS53603.1; -. [P62070-3]; . CCDS CCDS7814.1; -. [P62070-1]; . PIR B34788; TVHUC2; . RefSeq NP_001096139.1; NM_001102669.2. [P62070-2]; . RefSeq NP_001170785.1; NM_001177314.1. [P62070-3]; . RefSeq NP_001170786.1; NM_001177315.1. [P62070-2]; . RefSeq NP_036382.2; NM_012250.5. [P62070-1]; . UniGene Hs.502004; -; . UniGene Hs.712835; -; . PDB 2ERY; X-ray; 1.70 A; A/B=12-181 PDBsum 2ERY; -; . ProteinModelPortal P62070; -; . SMR P62070; -; . BioGrid 116480; 38; . IntAct P62070; 38; . MINT MINT-5001153; -; . STRING 9606.ENSP00000256196; -; . iPTMnet P62070; -; . PhosphoSitePlus P62070; -; . SwissPalm P62070; -; . BioMuta RRAS2; -; . DMDM 49065833; -; . EPD P62070; -; . MaxQB P62070; -; . PaxDb P62070; -; . PeptideAtlas P62070; -; . PRIDE P62070; -; . DNASU 22800; -; . Ensembl ENST00000256196; ENSP00000256196; ENSG00000133818. [P62070-1]; . Ensembl ENST00000414023; ENSP00000403282; ENSG00000133818. [P62070-2]; . Ensembl ENST00000526063; ENSP00000434104; ENSG00000133818. [P62070-2]; . Ensembl ENST00000529237; ENSP00000433230; ENSG00000133818. [P62070-2]; . Ensembl ENST00000532814; ENSP00000431954; ENSG00000133818. [P62070-2]; . Ensembl ENST00000534746; ENSP00000437083; ENSG00000133818. [P62070-2]; . Ensembl ENST00000537760; ENSP00000437547; ENSG00000133818. [P62070-3]; . GeneID 22800; -; . KEGG hsa:22800; -; . UCSC uc001mlf.5; human. [P62070-1]; . CTD 22800; -; . DisGeNET 22800; -; . GeneCards RRAS2; -; . HGNC HGNC:17271; RRAS2; . HPA CAB010420; -; . HPA HPA050942; -; . MIM 167000; phenotype; . MIM 600098; gene; . neXtProt NX_P62070; -; . OpenTargets ENSG00000133818; -; . PharmGKB PA34862; -; . eggNOG KOG0395; Eukaryota; . eggNOG COG1100; LUCA; . GeneTree ENSGT00860000133672; -; . HOGENOM HOG000233973; -; . HOVERGEN HBG009351; -; . InParanoid P62070; -; . KO K07830; -; . OMA CSAKLRI; -; . OrthoDB EOG091G0UAU; -; . PhylomeDB P62070; -; . TreeFam TF312796; -; . SignaLink P62070; -; . EvolutionaryTrace P62070; -; . GeneWiki RRAS2; -; . GenomeRNAi 22800; -; . PRO PR:P62070; -; . Proteomes UP000005640; Chromosome 11; . Bgee ENSG00000133818; -; . CleanEx HS_RRAS2; -; . ExpressionAtlas P62070; baseline and differential; . Genevisible P62070; HS; . GO GO:0005783; C:endoplasmic reticulum; NAS:ProtInc; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; NAS:ProtInc; . GO GO:0005525; F:GTP binding; IEA:UniProtKB-KW; . GO GO:0003924; F:GTPase activity; TAS:ProtInc; . GO GO:0001649; P:osteoblast differentiation; IDA:UniProtKB; . GO GO:0030335; P:positive regulation of cell migration; IEA:Ensembl; . GO GO:0007265; P:Ras protein signal transduction; IEA:Ensembl; . GO GO:1901214; P:regulation of neuron death; IMP:UniProtKB; . Gene3D 3.40.50.300; -; 1; . InterPro IPR027417; P-loop_NTPase; . InterPro IPR005225; Small_GTP-bd_dom; . InterPro IPR001806; Small_GTPase; . InterPro IPR020849; Small_GTPase_Ras; . PANTHER PTHR24070; PTHR24070; 1; . Pfam PF00071; Ras; 1; . SUPFAM SSF52540; SSF52540; 1; . TIGRFAMs TIGR00231; small_GTP; 1; . PROSITE PS51421; RAS; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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